Overview

  • Product name
    Recombinant Human OST-beta protein
  • Protein length
    Protein fragment

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MGSRSIQASR KEKMQPPEKE TPEVLHLDEA KDHNSLNNLR ETLLSEKPNL AQVELELKER DVLSVFLPDV PETES
    • Molecular weight
      11 kDa including tags
    • Amino acids
      57 to 128
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab171468 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    >95% by SDS-PAGE .
    ab171468 is purified using conventional chromatography techniques.
  • Form
    Liquid
  • Additional notes

    SLC51B, as known as OSTB, is an organic solute transporter subunit. SLC51 is composed of two distinct proteins that must heterodimerize to generate transport activity, but the role of the individual subunits in mediating transport activity is unknown. The results demonstrate that SLC51B is required for both proper trafficking of SLC51A and formation of the functional transport unit, and identify specific residues of SLC51B critical for these processes. Recombinant human SLC51B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride

General Info

  • Alternative names
    • Organic solute transporter subunit beta
    • OST-beta
    • OSTB
    • OSTB_HUMAN
  • Function
    Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. Efficiently transports the major species of bile acids.
  • Tissue specificity
    Widely expressed with a high expression in ileum. Expressed in testis, colon, liver, small intestine, kidney, ovary and adrenal gland; and at low levels in heart, lung, brain, pituitary, thyroid gland, uterus, prostate, mammary gland and fat.
  • Sequence similarities
    Belongs to the OST-beta family.
  • Cellular localization
    Cell membrane. Mainly restricted to the lateral and basal membranes of ileal enterocytes.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab171468 (3µg).

References

ab171468 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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