Description

  • Product name

    Recombinant Human p18 INK4c/CDKN2C protein
    See all p18 INK4c/CDKN2C proteins and peptides
  • Purity

    > 90 % SDS-PAGE.
    Purity was determined to be >90% by densitometry.
  • Expression system

    Escherichia coli
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab85605 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

     This product was previously labelled as p18 INK4c

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 25% Glycerol, 0.87% Sodium chloride

General Info

  • Alternative names

    • CDK6 inhibitor p18
    • CDKN 2C
    • CDKN 6
    • Cdkn2c
    • CDKN6
    • CDN2C_HUMAN
    • Cyclin dependent inhibitor
    • Cyclin dependent kinase 4 inhibitor C
    • Cyclin dependent kinase 6 inhibitor
    • Cyclin dependent kinase 6 inhibitor p18
    • Cyclin dependent kinase inhibitor 2C
    • Cyclin dependent kinase inhibitor 2C (p18 inhibits CDK4)
    • Cyclin-dependent kinase 4 inhibitor C
    • Cyclin-dependent kinase 6 inhibitor
    • INK4C
    • OTTHUMP00000046546
    • p18
    • p18 inhibits CDK4
    • p18 INK4c
    • p18 INK6
    • p18-INK4c
    • p18-INK6
    see all
  • Function

    Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.
  • Tissue specificity

    Highest levels found in skeletal muscle. Also found in pancreas and heart.
  • Sequence similarities

    Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.
    Contains 4 ANK repeats.
  • Information by UniProt

Images

  • SDS-PAGE showing ab85605 at approximately 42kDa.

References

ab85605 has not yet been referenced specifically in any publications.

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