Overview

  • Product name

    Recombinant Human P4HA3 protein
  • Protein length

    Protein fragment

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Molecular weight

      31 kDa
    • Amino acids

      130 to 396
    • Tags

      His-DHFR tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127112 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration

General Info

  • Alternative names

    • 2-oxoglutarate-4-dioxygenase subunit alpha-3
    • 4-PH alpha-3
    • P4ha3
    • P4HA3_HUMAN
    • Procollagen-proline
    • Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III
    • Procollagen-proline, 2-oxoglutarate 4-dioxygenase, alpha subunit, isoform 3
    • Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3
    • Prolyl 4-hydroxylase subunit alpha-3
    • Prolyl 4-hydroxylase, alpha polypeptide III
    • Prolyl 4-hydroxylase, alpha-3 subunit
    see all
  • Function

    Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
  • Tissue specificity

    Highly expressed in placenta, liver and fetal skin. Weakly expressed in fetal epiphyseal cartilage, fetal liver, fibroblast, lung and skeletal muscle. Expressed also in fibrous cap of carotid atherosclerotic lesions.
  • Sequence similarities

    Belongs to the P4HA family.
    Contains 1 Fe2OG dioxygenase domain.
    Contains 1 TPR repeat.
  • Post-translational
    modifications

    N-glycosylation plays no role in the catalytic activity.
  • Cellular localization

    Endoplasmic reticulum lumen.
  • Information by UniProt

References

ab127112 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab127112.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up