Recombinant Human PAF Receptor coexpressed with Gia1, β1 and gamma 2 protein (ab90402)

Description

  • Product name

    Recombinant Human PAF Receptor coexpressed with Gia1, β1 and gamma 2 protein
  • Expression system

    Baculovirus infected Sf9 cells
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Predicted molecular weight

      114 kDa including tags
    • Tags

      His tag C-Terminus , DDDDK tag N-Terminus
  • Description

    Recombinant Human PAF Receptor coexpressed with Gia1, ß1 and gamma 2 protein

Specifications

Our Abpromise guarantee covers the use of ab90402 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.40
    Constituents: 0.11875% Magnesium chloride, 1.185% Tris HCl, 0.0292% EDTA

General Info

  • Alternative names

    • PAF R
    • PAFR
    • Platelet activating factor receptor
  • Relevance

    The PAF receptor binds platelet-activating factor (PAF) and is thought to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. PAF is a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. It has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes. The PAF receptor is induced by granulocyte macrophage colony-stimulating factor (GM-CSF), interleukin-5 and n-butyrate. A diverse range of compounds act as PAF receptor antagonists; these may be useful pharmacologically.
  • Cellular localization

    Cell Membrane

References

ab90402 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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