Overview

Description

  • Nature

    Recombinant
  • Source

    Wheat germ
  • Amino Acid Sequence
    • Species

      Human
    • Sequence

      MKLINGKKQTFPWFGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRK YLTSNTAYGKTGIRDVHLELKNLTMCGRKGNLHFIRFPSCAMHRFIQMGS EKNFSSLHTTLCATGGGAFKFEEDFRMIADLQLHKLDELDCLIQGLLYVD SVGFNGKPECYYFENPTNPELCQKKPYCLDNPYPMLLVNMGSGVSILAVY SKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMAAKGDSTNVDKLV KDIYGGDYERFGLQGSAVASSFGNMMSKEKRDSISKEDLARATLVTITNN IGSIARMCALNENIDRVVFVGNFLRINMVSMKLLAYAMDFWSKGQLKALF LEHEGYFGAVGALLELFKMTDDK
    • Amino acids

      1 to 373
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab153362 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • coaA
    • hPanK
    • hPanK1
    • PANK
    • PANK1
    • PANK1_HUMAN
    • PANK1a
    • PANK1b
    • PanK1beta
    • Pantothenate kinase
    • Pantothenate kinase 1
    • Pantothenic acid kinase 1
    see all
  • Function

    Plays a role in the physiological regulation of the intracellular CoA concentration.
  • Tissue specificity

    Isoform 1 is expressed at high levels in brain, heart, kidney, liver, skeletal muscle and testis. Isoform 2 is detected at much lower levels in kidney, liver, brain and testis and is not detected in heart or skeletal muscle.
  • Pathway

    Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.
  • Sequence similarities

    Belongs to the type II pantothenate kinase family.
  • Domain

    The N-terminal extension, present in isoform 1 may be the regulatory domain.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt

Images

  • ab153362 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab153362 has not yet been referenced specifically in any publications.

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