Recombinant Human Parathyroid Hormone Receptor 1/PTH1R protein (His tag) (ab182670)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 85% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Tags: His tag C-Terminus
- Suitable for: SDS-PAGE
Description
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Product name
Recombinant Human Parathyroid Hormone Receptor 1/PTH1R protein (His tag)
See all Parathyroid Hormone Receptor 1/PTH1R proteins and peptides -
Purity
> 85 % SDS-PAGE. -
Endotoxin level
< 1.000 Eu/µg -
Expression system
HEK 293 cells -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
DADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPASIMESDKGWTSASTSG KPRKDKASGKLYPESEEDKEAPTGSRYRGRPCLPEWDHILCWPLGAPGEV VAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTN ETREREVFDRLG -
Predicted molecular weight
20 kDa including tags -
Amino acids
27 to 188 -
Tags
His tag C-Terminus -
Additional sequence information
Extracellular domain. NP_000307.
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab182670 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Lyophilized -
Additional notes
This product was previously labelled as Parathyroid Hormone Receptor 1.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituents: 95% PBS, 5% Trehalose
Lyophilized from 0.22 µm filtered solution. -
ReconstitutionReconstitute with sterile deionized water to a concentration of 200 µg/ml.
General Info
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Alternative names
- MGC138426
- MGC138452
- Parathyroid hormone 1 receptor
see all -
Function
Receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. -
Tissue specificity
Expressed in most tissues. Most abundant in kidney, bone and liver. -
Involvement in disease
Jansen metaphyseal chondrodysplasia
Chondrodysplasia Blomstrand type
Enchondromatosis multiple
Eiken skeletal dysplasia
Primary failure of tooth eruption -
Sequence similarities
Belongs to the G-protein coupled receptor 2 family. -
Cellular localization
Cell membrane. - Information by UniProt
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab182670 has not yet been referenced specifically in any publications.