The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
p53 associated parkin like cytoplasmic protein
p53-associated parkin-like cytoplasmic protein
parkin-like cytoplasmic p53 binding protein
UbcH 7 associated protein 1
UbcH7 associated protein 1
UbcH7-associated protein 1
Cytoplasmic anchor protein in p53-associated protein complex. Regulates the subcellular localization of p53 and subsequent function. Seems to be part of an atypical cullin-RING-based E3 ubiquitin-protein ligase complex. In vitro, complexes of CUL9/PARC with either CUL7 or TP53 contain E3 ubiquitin-protein ligase activity.
Ubiquitously expressed in all tissues with highest expression in testis brain and kidney.
Belongs to the cullin family. Contains 1 DOC domain. Contains 1 IBR-type zinc finger. Contains 2 RING-type zinc fingers.
The IBR domain is required for interaction with UBCH7 and UBCH8.
In vitro, self-ubiquitination in the presence of E1, E2 and ubiquitin. Neddylated.