Recombinant Human PCGF6 protein (ab198485)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: >= 86% SDS-PAGE
- Tags: GST tag N-Terminus
- Suitable for: Functional Studies, SDS-PAGE
Description
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Product name
Recombinant Human PCGF6 protein -
Purity
>= 86 % SDS-PAGE.
Affinity purified. -
Expression system
Baculovirus infected Sf9 cells -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGL EFPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVL DIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFKDRLCHKTYLNGDHVTH PDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIA WPLQGWQATFGGGDHPPKSDPLVPRGSPGEFEGVAVVTAGSVGAAKTEGA AALPPPPPVSPPALTPAPAAGEEGPAPLSETGAPGCSGSRPPE LEPER SLGRFRGRFEDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQD SE DEEERLINLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYS NRCPK CNIVVHQTQPLYNIRLDRQLQDIVYKLVINLEEREKKQMHDFY KERGLEVPKPAVPQPVPSSKGRSKKVLESVFRIPPELDMSLLLEFIGANE GTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLDPACQVDIICGDHLLE QYQTLREIRRAIGDAAMQDGLLVLHYGLVVSPLKIT -
Predicted molecular weight
66 kDa including tags -
Amino acids
2 to 350 -
Tags
GST tag N-Terminus -
Additional sequence information
GST-linker (PLVPRGSPGEF)-RING6a protein. NM_001011663.1.
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Specifications
Our Abpromise guarantee covers the use of ab198485 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Functional Studies
SDS-PAGE
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Form
Liquid -
Additional notes
ab198485 is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
This product was previously labelled as RING6a
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.48% Tris, 0.64% Sodium chloride, 0.02% Potassium chloride, 0.04% Tween, 20% Glycerol (glycerin, glycerine)
General Info
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Alternative names
- MBLR
- Mel18 and Bmi1 like RING finger protein
- Mel18 and Bmi1-like RING finger
see all -
Function
Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. -
Tissue specificity
Ubiquitous. -
Sequence similarities
Contains 1 RING-type zinc finger. -
Post-translational
modificationsPhosphorylated during mitosis. Phosphorylated on Ser-30 by CDK7 in vitro. -
Cellular localization
Nucleus. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab198485 has not yet been referenced specifically in any publications.