Function: Catalyzes the methyl esterification of L-isoaspartyl and D-aspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. Acts on EIF4EBP2, microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin carboxyl-terminal hydrolase isozyme L1, phosphatidylethanolamine-binding protein 1, stathmin, beta-synuclein and alpha-synuclein.
Similarity: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
SDS-PAGE - Recombinant Human PCMT1 protein (ab95914)
15% SDS-PAGE showing ab95914 at approximately 28.8kDa (3µg).
has not yet been referenced specifically in any publications.
Publishing research using ab95914? Please let us know so that we can cite the reference in this datasheet.
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