Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      (PCTAIRE1) RKISTEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKP LSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALK EIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLD KDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLI NERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQID MWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEE FKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHP FFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDSGRPAFRVVDT EF (Cyclin Y) GNTTSCCVSSSPKLRRNAHSRLESYRPDTDLSREDTGCNLQHISDR ENIDDLNMEFNPSDHPRASTIFLSKSQTDVREKRKSLFINHHPPGQIARK YSSCSTIFLDDSTVSQPNLKYTIKCVALAIYYHIKNRDPDGRMLLDIFDE NLHPLSKSEVPPDYDKHNPEQKQIYRFVRTLFSAAQLTAECAIVTLVYLE RLLTYAEIDICPANWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVE DMNELERQFLELLQFNINVPSSVYAKYYFDLRSLAEANNLSFPLEPLSRE RAHKLEAISRLCEDKYKDLRRSARKRSASADNLTLPRWSPAIIS
    • Molecular weight
      66 kDa including tags
    • Amino acids
      107 to 496
    • Tags
      proprietary tag N-Terminus
    • Additional sequence information
      Cyclin Y accession number is NM_145012 (aa 2-341) . Molecular weight is 64 kDa including N terminal proprietary tag.

Specifications

Our Abpromise guarantee covers the use of ab177586 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity

    The specific activity of ab177586 was determined to be 40 nmol/mim/mg.

  • Applications

    SDS-PAGE

    Functional Studies

    Western blot

  • Purity
    >90% by SDS-PAGE.

  • Form
    Liquid
  • Additional notes

    ab56270 (Human Rb protein fragment), ab89813 (Histone H1 protein) and ab64311 (Myelin Basic Protein protein) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

    Information available upon request.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Cdk16
    • CDK16_HUMAN
    • Cell division protein kinase 16
    • Cyclin-dependent kinase 16
    • PCTAIRE
    • PCTAIRE protein kinase 1
    • PCTAIRE-motif protein kinase 1
    • PCTAIRE1
    • PCTGAIRE
    • PCTK1
    • Serine/threonine-protein kinase PCTAIRE-1
    see all
  • Function
    May play a role in signal transduction cascades in terminally differentiated cells.
  • Sequence similarities
    Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
    Contains 1 protein kinase domain.
  • Information by UniProt

Images

  • The purity of ab177586 was determined to be >90% by densitometry.

  • The specific activity of ab177586 was determined to be 40 nmol/mim/mg.

References

ab177586 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab177586.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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