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Recombinant Human PD-L1 protein (ab112410)

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SDS-PAGE - Recombinant Human PD-L1 protein (ab112410)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: ELISA, PepArr, WB

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    Description

    • Product name

      Recombinant Human PD-L1 protein
      See all PD-L1 proteins and peptides
    • Biological activity

      This product is useful for Antibody Production and Protein Array
    • Expression system

      Wheat germ
    • Accession

      Q9NZQ7
    • Protein length

      Protein fragment
    • Animal free

      No
    • Nature

      Recombinant
      • Species

        Human
      • Sequence

        ILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTTTTNSKREEKL FNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTH
      • Predicted molecular weight

        37 kDa including tags
      • Amino acids

        141 to 240
      • Tags

        GST tag N-Terminus

    Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab112410 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        ELISA

        Peptide Array

        Western blot

      • Form

        Liquid
      • Additional notes

        This product is useful for Antibody Production and Protein Array.

         

      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

        pH: 8.00
        Constituents: 0.31% Glutathione, 0.79% Tris HCl

        Glutathione is reduced.

      General Info

      • Alternative names

        • B7 H
        • B7 H1
        • B7 homolog 1
        • B7-H1
        • B7H
        • B7H1
        • CD 274
        • CD274
        • CD274 antigen
        • CD274 molecule
        • MGC142294
        • MGC142296
        • OTTHUMP00000021029
        • PD L1
        • PD-L1
        • PD1L1_HUMAN
        • PDCD1 ligand 1
        • PDCD1L1
        • PDCD1LG1
        • PDL 1
        • PDL1
        • Programmed cell death 1 ligand 1
        • Programmed death ligand 1
        • RGD1566211
        see all
      • Function

        Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
      • Tissue specificity

        Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes.
      • Sequence similarities

        Belongs to the immunoglobulin superfamily. BTN/MOG family.
        Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
        Contains 1 Ig-like V-type (immunoglobulin-like) domain.
      • Cellular localization

        Cell membrane and Endomembrane system.
      • Target information above from: UniProt accession Q9NZQ7 The UniProt Consortium
        The Universal Protein Resource (UniProt) in 2010
        Nucleic Acids Res. 38:D142-D148 (2010) .

        Information by UniProt

      Images

      • SDS-PAGE - Recombinant Human PD-L1 protein (ab112410)
        SDS-PAGE - Recombinant Human PD-L1 protein (ab112410)
        12.5% SDS-PAGE image, using ab112410. (Stained with Coomassie Blue).

      Protocols

      To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

      Click here to view the general protocols

      Datasheets and documents

      • Datasheet
    • References (0)

      Publishing research using ab112410? Please let us know so that we can cite the reference in this datasheet.

      ab112410 has not yet been referenced specifically in any publications.

      Customer reviews and Q&As

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      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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