Recombinant Human PD-L1 protein (ab112410)

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Description

  • Product name

    Recombinant Human PD-L1 protein
    See all PD-L1 proteins and peptides

  • Biological activity

    This product is useful for Antibody Production and Protein Array

  • Expression system

    Wheat germ

  • Accession

    Q9NZQ7

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      ILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTTTTNSKREEKL FNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTH

    • Predicted molecular weight

      37 kDa including tags

    • Amino acids

      141 to 240

    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab112410 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Peptide Array

    Western blot

  • Form

    Liquid

  • Additional notes

    Best used within three months from the date of receipt This product is useful for Antibody Production and Protein Array
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione
    Note: Glutathione is reduced.

General Info

  • Alternative names

    • B7 H
    • B7 H1
    • B7 homolog 1
    • B7-H1
    • B7H
    • B7H1
    • CD 274
    • CD274
    • CD274 antigen
    • CD274 molecule
    • MGC142294
    • MGC142296
    • OTTHUMP00000021029
    • PD L1
    • PD-L1
    • PD1L1_HUMAN
    • PDCD1 ligand 1
    • PDCD1L1
    • PDCD1LG1
    • PDL 1
    • PDL1
    • Programmed cell death 1 ligand 1
    • Programmed death ligand 1
    • RGD1566211
    see all

  • Function

    Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.

  • Tissue specificity

    Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes.

  • Sequence similarities

    Belongs to the immunoglobulin superfamily. BTN/MOG family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.

  • Cellular localization

    Cell membrane and Endomembrane system.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human PD-L1 protein (ab112410)
    SDS-PAGE - Recombinant Human PD-L1 protein (ab112410)
    12.5% SDS-PAGE image, using ab112410. (Stained with Coomassie Blue).

References

ab112410 has not yet been referenced specifically in any publications.

Publishing research using ab112410? Please let us know so that we can cite the reference in this datasheet.

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