Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 90% Densitometry
- Active: Yes
- Tags: His tag N-Terminus
- Suitable for: Functional Studies, SDS-PAGE
Product nameRecombinant human PDE1A protein
Biological activityThe specific activity of ab125661 was determined to be 12250 - 12290 nmol/min/mg.
Purity> 90 % Densitometry.
Purity was determined to be >90% by densitometry.
Expression systemBaculovirus infected Sf9 cells
Protein lengthFull length protein
Predicted molecular weight64 kDa including tags
Amino acids2 to 545
TagsHis tag N-Terminus
Our Abpromise guarantee covers the use of ab125661 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Preservative: 1.02% Imidazole
Constituents: 1.05% MOPS, 0.002% PMSF, 0.004% DTT, 25% Glycerol (glycerin, glycerine), 1.75% Sodium chloride
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- 3' 5' cyclic nucleotide phosphodiesterase
- 5''-cyclic nucleotide phosphodiesterase 1A
- 61 kDa Cam PDE
FunctionCyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP.
Tissue specificitySeveral tissues, including brain, kidney, testes and heart.
Sequence similaritiesBelongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab125661 has not yet been referenced specifically in any publications.