Recombinant human PDE1A protein (ab125661)
- Datasheet
- References
- Protocols
Overview
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Product nameRecombinant human PDE1A protein
See all PDE1A proteins and peptides -
Protein lengthFull length protein
Description
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NatureRecombinant
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SourceBaculovirus infected Sf9 cells
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Amino Acid Sequence
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Accession
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SpeciesHuman
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Molecular weight64 kDa including tags
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Amino acids2 to 545
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TagsHis tag N-Terminus
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab125661 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Biological activityThe specific activity of ab125661 was determined to be 12250 - 12290 nmol/min/mg.
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Applications
Functional Studies
SDS-PAGE
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Purity> 90 % Densitometry.
Purity was determined to be >90% by densitometry. -
FormLiquid
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.00
Preservative: 1.02% Imidazole
Constituents: 1.05% MOPS, 0.002% PMSF, 0.004% DTT, 25% Glycerol, 1.75% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
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Alternative names
- 3' 5' cyclic nucleotide phosphodiesterase
- 5''-cyclic nucleotide phosphodiesterase 1A
- 61 kDa Cam PDE
see all -
FunctionCyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP.
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Tissue specificitySeveral tissues, including brain, kidney, testes and heart.
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Sequence similaritiesBelongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
- Information by UniProt
Images
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SDS-PAGE - Recombinant human PDE1A protein (ab125661)SDS-PAGE analysis of ab125661. -
Functional Studies - Recombinant human PDE1A protein (ab125661)Sample Phosphodiesterase Assay showing the specific activity of ab125661 as 12250 nmol/min/mg.
References
ab125661 has not yet been referenced specifically in any publications.
