Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Accession
      Q14432
    • Species
      Human
    • Molecular weight
      84 kDa
    • Amino acids
      669 to 1141
    • Tags
      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab125545 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    The specific activity of ab125545 was determined to be 500 nmol/min/mg as per activity assay protocol.
  • Applications

    Functional Studies

    SDS-PAGE

  • Purity
    > 85 % SDS-PAGE.
    Assessed by densitometry.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 25% Glycerol, 0.88% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • 5''-cyclic phosphodiesterase A
    • cAMP phosphodiesterase myocardial cGMP inhibited
    • CGI PDE
    • CGI PDE A
    • CGI-PDE A
    • cGMP inhibited 3' 5' cyclic phosphodiesterase A
    • cGMP-inhibited 3''
    • Cyclic GMP inhibited phosphodiesterase A
    • Cyclic GMP-inhibited phosphodiesterase A
    • Human cGMP inhibited cAMP phosphodiesterase mRNA
    • PDE 3A
    • Pde3a
    • PDE3A_HUMAN
    • Phosphodiesterase 3A
    • Phosphodiesterase 3A cGMP inhibited
    see all
  • Function
    Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.
  • Sequence similarities
    Belongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily.
  • Cellular localization
    Membrane.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant human PDE3A protein (ab125545)
    SDS-PAGE - Recombinant human PDE3A protein (ab125545)
    SDS-PAGE analysis of ab125545.
  • Functional Studies - Recombinant human PDE3A protein (ab125545)
    Functional Studies - Recombinant human PDE3A protein (ab125545)
    The specific activity of ab125545 was determined to be 500nmol/min/mg.

References

ab125545 has not yet been referenced specifically in any publications.

Publishing research using ab125545? Please let us know so that we can cite the reference in this datasheet.

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