Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 82% SDS-PAGE
- Active: Yes
- Tags: His tag N-Terminus, GST tag N-Terminus
- Suitable for: Functional Studies, SDS-PAGE
Product nameRecombinant human PDE3A protein
See all PDE3A proteins and peptides
Specific Activity: ≥ 4000 pmol/min/µl
Purity> 82 % SDS-PAGE.
Expression systemBaculovirus infected Sf9 cells
Protein lengthProtein fragment
SequenceKPILAPEPLVMDNLDSIMEQLNTWNFPIFDLVENIGRKCGRILSQVSYRL FEDMGLFEAFKIPIREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLT TQPIPGLSTVINDHGSTSDSDSDSGFTHGHMGYVFSKTYNVTDDKYGCLS GNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENH HAAAAWNLFMSRPEYNFLINLDHVEFKHFRFLVIEAILATDLKKHFDFVA KFNGKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLQWTDGI VNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDS AGLMPGKWVEDSDESGDTDDPEEEEEEAPAPNEEETCENNESPKKKTFKR RKIYCQITQHLLQNHKMWKKVIEEEQRLAGIENQSLDQTPQSHSSEQIQA IKEEEEEKGKPRGEEIPTQKPDQ
Predicted molecular weight82 kDa including tags
Amino acids669 to 1141
TagsHis tag N-Terminus , GST tag N-Terminus
Our Abpromise guarantee covers the use of ab198445 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.
Constituents: 0.63% Tris HCl, 0.64% Sodium chloride, 0.02% Potassium chloride, 0.05% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 20% Glycerol (glycerin, glycerine), 0.49% Glutathione
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- 5''-cyclic phosphodiesterase A
- cAMP phosphodiesterase myocardial cGMP inhibited
- CGI PDE
FunctionCyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.
Sequence similaritiesBelongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab198445 has not yet been referenced specifically in any publications.