Recombinant human PDE4C protein (ab125647)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 80% Densitometry
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
Description
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Product name
Recombinant human PDE4C protein -
Biological activity
The specific activity of ab125647 was determined to be 83 nmol/min/mg. -
Purity
> 80 % Densitometry. -
Expression system
Baculovirus infected Sf9 cells -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Predicted molecular weight
75 kDa including tags -
Amino acids
287 to 712
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab125647 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Functional Studies
SDS-PAGE
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Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.002% PMSF, 0.005% DTT, 0.79% Tris HCl, 25% Glycerol (glycerin, glycerine), 0.88% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
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Alternative names
- 5''-cyclic phosphodiesterase 4C
- cAMP specific 3' 5' cyclic phosphodiesterase 4C
- cAMP-specific 3''
see all -
Function
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. -
Tissue specificity
Expressed in various tissues but not in cells of the immune system. -
Pathway
Purine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1. -
Sequence similarities
Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily. - Information by UniProt
Images
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Functional Studies - Recombinant human PDE4C protein (ab125647)The specific activity of PDE4C (ab125647) was determined to be 71.2 nmol/min/mg as per activity assay protocol
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SDS-PAGE - Recombinant human PDE4C protein (ab125647)SDS PAGE analysis of ab125647 -
SDS-PAGE - Recombinant human PDE4C protein (ab125647)SDS PAGE analysis of ab125647 -
SDS-PAGE - Recombinant human PDE4C protein (ab125647)SDS-PAGE analysis of ab125647. -
Functional Studies - Recombinant human PDE4C protein (ab125647)Sample assay showing the specific activity of ab125647 to be 83 nmol/min/mg.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab125647 has not yet been referenced specifically in any publications.
