Recombinant human PDE4C protein (ab125647)

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Description

  • Product name

    Recombinant human PDE4C protein

  • Biological activity

    The specific activity of ab125647 was determined to be 83 nmol/min/mg.

  • Purity

    > 80 % Densitometry.

  • Expression system

    Baculovirus infected Sf9 cells

  • Accession

    Q08493

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Predicted molecular weight

      75 kDa including tags

    • Amino acids

      287 to 712

Specifications

Our Abpromise guarantee covers the use of ab125647 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.002% PMSF, 0.005% DTT, 0.79% Tris HCl, 25% Glycerol, 0.88% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names

    • 5''-cyclic phosphodiesterase 4C
    • cAMP specific 3' 5' cyclic phosphodiesterase 4C
    • cAMP-specific 3''
    • DPDE 1
    • DPDE1
    • MGC126222
    • PDE 21
    • PDE 4C
    • PDE21
    • Pde4c
    • PDE4C_HUMAN
    • Phosphodiesterase 4C
    • Phosphodiesterase 4C cAMP specific
    • Phosphodiesterase 4C, cAMP specific (phosphodiesterase E1 dunce homolog, Drosophila)
    • Phosphodiesterase E1 dunce homolog
    • Phosphodiesterase E1 dunce homolog Drosophila
    • Phosphodiesterase type 4C
    see all

  • Function

    Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.

  • Tissue specificity

    Expressed in various tissues but not in cells of the immune system.

  • Pathway

    Purine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1.

  • Sequence similarities

    Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
  • Information by UniProt

Images

  • Functional Studies - Recombinant human PDE4C protein (ab125647)
    Functional Studies - Recombinant human PDE4C protein (ab125647)
    The specific activity of PDE4C (ab125647) was determined to be 71.2 nmol/min/mg as per activity assay protocol
  • SDS-PAGE - Recombinant human PDE4C protein (ab125647)
    SDS-PAGE - Recombinant human PDE4C protein (ab125647)
    SDS PAGE analysis of ab125647
  • SDS-PAGE - Recombinant human PDE4C protein (ab125647)
    SDS-PAGE - Recombinant human PDE4C protein (ab125647)
    SDS PAGE analysis of ab125647
  • SDS-PAGE - Recombinant human PDE4C protein (ab125647)
    SDS-PAGE - Recombinant human PDE4C protein (ab125647)
    SDS-PAGE analysis of ab125647.
  • Functional Studies - Recombinant human PDE4C protein (ab125647)
    Functional Studies - Recombinant human PDE4C protein (ab125647)
    Sample assay showing the specific activity of ab125647 to be 83 nmol/min/mg.

References

ab125647 has not yet been referenced specifically in any publications.

Publishing research using ab125647? Please let us know so that we can cite the reference in this datasheet.

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