Overview

  • Product name
    Recombinant Human PDE4DIP protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MFLCQGFRKYLPEHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYRR NTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQE TEHVYELLENKMQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGV TKNWEDVPGDQVKPDQYTEALAQRDKI
    • Amino acids
      1 to 177
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab160600 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Cardiomyopathy associated protein 2
    • Cardiomyopathy-associated protein 2
    • CMYA2
    • MMGL
    • MYOME_HUMAN
    • Myomegalin
    • Pde4dip
    • Phosphodiesterase 4D interacting protein
    • Phosphodiesterase 4D-interacting protein
    see all
  • Function
    May function as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes.
  • Tissue specificity
    Highly expressed in heart and skeletal muscle and to a lower extent in brain and placenta.
  • Involvement in disease
    Note=A chromosomal aberration involving PDE4DIP may be the cause of a myeloproliferative disorder (MBD) associated with eosinophilia. Translocation t(1;5)(q23;q33) that forms a PDE4DIP-PDGFRB fusion protein.
  • Sequence similarities
    Contains 1 NBPF domain.
  • Developmental stage
    Expressed in fetal heart.
  • Cellular localization
    Golgi apparatus. Cytoplasm > cytoskeleton > centrosome. Cytoplasm. Nucleus.
  • Information by UniProt

Images

  • ab160600 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab160600 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab160600.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up