Overview

Description

  • Nature

    Recombinant
  • Source

    Baculovirus
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Molecular weight

      66 kDa
    • Amino acids

      109 to 450
    • Tags

      His tag C-Terminus , GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab79800 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity

    Specific Activity: 53 pmol/min/µg.
  • Applications

    Functional Studies

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.0462% DTT, 0.395% Tris HCl, 0.05% Tween, 50% Glycerol, 0.58% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names

    • bA472E5.1
    • cAMP specific 3 5 cyclic phosphodiesterase 7B
    • cAMP specific 3'5' cyclic phosphodiesterase 7B
    • High affinity cAMP specific 3 5 cyclic phosphodiesterase
    • High affinity cAMP specific 3'5' cyclic phosphodiesterase
    • MGC88256
    • OTTHUMP00000017267
    • PDE 7B
    • PDE7B protein
    • Phosphodiesterase 7B
    • Phosphodiesterase7B
    • RNPDE7B
    • Rolipram insensitive phosphodiesterase type 7
    see all
  • Relevance

    PDE7B is a cAMP specific phosphodiesterase. The cAMP-specific phosphodiesterase type-7 (PDE7) family is comprised of 2 genes (PDE7A and PDE7B) each with multiple splice variants generated by RNA splicing and use of alternate initiation sites. PDE7B has three splice variants (PDE7B1 = 446 amino acid; PDE7B2 =359 amino acids and PDE7B3 = 459 amino acids. Both PDE7B2 ad PDE7B3 posses unique N-terminal sequences. PDE7B is expressed in various tissues including skeletal muscle, heart, lung and testis. PDE7B may be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain.
  • Cellular localization

    cytosol

Images

  • 10% SDS-PAGE, Coomassie staining.
    Lane 1: ab79800, 4µg.
    Lane 2: Protein marker.
  • Image showing specific activity of ab79800.

References

ab79800 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab79800.
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