Recombinant Human PDE9A protein (ab159078)

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SDS-PAGE - Recombinant Human PDE9A protein (ab159078)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: ELISA, WB

    Description

    • Product name

      Recombinant Human PDE9A protein
      See all PDE9A proteins and peptides

    • Expression system

      Wheat germ

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTT ISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQV AEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMRE ELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPT FDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNP FHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFK QIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKC CDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKA TAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAM KELQKKTDSLTSGATEKSRERSRDVKNSEGDCA

      • Amino acids

        1 to 533

      • Tags

        GST tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab159078 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      ELISA

      Western blot

    • Form

      Liquid

    • Additional notes

       

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • 5''-cyclic phosphodiesterase 9A
      • cGMP specific 3' 5' cyclic phosphodiesterase type 9
      • FLJ90181
      • High affinity cGMP-specific 3''
      • High-affinity cGMP-specific 3'5'-cyclic phosphodiesterase 9A
      • HSPDE9A2
      • OTTHUMP00000109399
      • PDE 9A
      • Pde9a
      • PDE9A_HUMAN
      • Phosphodiesterase 9A
      • phosphodiesterase PDE9A21
      see all

    • Function

      Hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes.

    • Tissue specificity

      Expressed in all tissues examined (testis, brain, small intestine, skeletal muscle, heart, lung, thymus, spleen, placenta, kidney, liver, pancreas, ovary and prostate) except blood. Highest levels in brain, heart, kidney, spleen, prostate and colon. Isoform PDE9A12 is found in prostate.

    • Sequence similarities

      Belongs to the cyclic nucleotide phosphodiesterase family. PDE9 subfamily.

    • Domain

      Composed of a C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain.

    • Cellular localization

      Cytoplasm. Endoplasmic reticulum; Cell projection > ruffle membrane. Cytoplasm > perinuclear region and Cell projection > ruffle membrane. Cytoplasm > perinuclear region. Golgi apparatus. Endoplasmic reticulum.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human PDE9A protein (ab159078)
      SDS-PAGE - Recombinant Human PDE9A protein (ab159078)
      ab159078 on a 12.5% SDS-PAGE stained with Coomassie Blue.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab159078? Please let us know so that we can cite the reference in this datasheet.

    ab159078 has not yet been referenced specifically in any publications.

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