Recombinant Human PDE9A protein (ab159078)

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Description

  • Product name

    Recombinant Human PDE9A protein
    See all PDE9A proteins and peptides

  • Expression system

    Wheat germ

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTT ISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQV AEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMRE ELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPT FDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNP FHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFK QIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKC CDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKA TAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAM KELQKKTDSLTSGATEKSRERSRDVKNSEGDCA

    • Amino acids

      1 to 533

    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab159078 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid

  • Additional notes

     

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • 5''-cyclic phosphodiesterase 9A
    • cGMP specific 3' 5' cyclic phosphodiesterase type 9
    • FLJ90181
    • High affinity cGMP-specific 3''
    • High-affinity cGMP-specific 3'5'-cyclic phosphodiesterase 9A
    • HSPDE9A2
    • OTTHUMP00000109399
    • PDE 9A
    • Pde9a
    • PDE9A_HUMAN
    • Phosphodiesterase 9A
    • phosphodiesterase PDE9A21
    see all

  • Function

    Hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes.

  • Tissue specificity

    Expressed in all tissues examined (testis, brain, small intestine, skeletal muscle, heart, lung, thymus, spleen, placenta, kidney, liver, pancreas, ovary and prostate) except blood. Highest levels in brain, heart, kidney, spleen, prostate and colon. Isoform PDE9A12 is found in prostate.

  • Sequence similarities

    Belongs to the cyclic nucleotide phosphodiesterase family. PDE9 subfamily.

  • Domain

    Composed of a C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain.

  • Cellular localization

    Cytoplasm. Endoplasmic reticulum; Cell projection > ruffle membrane. Cytoplasm > perinuclear region and Cell projection > ruffle membrane. Cytoplasm > perinuclear region. Golgi apparatus. Endoplasmic reticulum.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human PDE9A protein (ab159078)
    SDS-PAGE - Recombinant Human PDE9A protein (ab159078)
    ab159078 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab159078 has not yet been referenced specifically in any publications.

Publishing research using ab159078? Please let us know so that we can cite the reference in this datasheet.

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