Description

  • Product name

    Recombinant Human PDHX protein (His tag)
  • Purity

    > 85 % SDS-PAGE.
    ab202213 was purified using conventional chromatography.
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSGDPIKIL MPSLSPTMEE GNIVKWLKKE GEAVSAGDAL CEIETDKAVV TLDASDDGIL AKIVVEEGSK NIRLGSLIGL IVEEGEDWKH VEIPKDVGPP PPVSKPSEPR PSPEPQISIP VKKEHIPGTL RFRLSPAARN ILEKHSLDAS QGTATGPRGI FTKEDALKLV QLKQTGKITE SRPTPAPTAT PTAPSPLQAT AGPSYPRPVI PPVSTPGQPN AVGTFTEIPA SNIRRVIAKR LTESKSTVPH AYATADCDLG AVLKVRQDLV KDDIKVSVND FIIKAAAVTL KQMPDVNVSW DGEGPKQLPF IDISVAVATD KGLLTPIIKD AAAKGIQEIA DSVKALSKKA RDGKLLPEEY QGGSFSISNL GMFGIDEFTA VINPPQACIL AVGRFRPVLK LTEDEEGNAK LQQRQLITVT MSSDSRVVDD ELATRFLKSF KANLENPIRL A
    • Predicted molecular weight

      50 kDa including tags
    • Amino acids

      54 to 501
    • Tags

      His tag N-Terminus
    • Additional sequence information

      This is the full length mature protein without the transit peptide. NCBI Accession No.: NP_003468.

Specifications

Our Abpromise guarantee covers the use of ab202213 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.4
    Constituents: 89% PBS, 20% Glycerol, 0.02% DTT

General Info

  • Alternative names

    • Dihydrolipoamide dehydrogenase binding protein of pyruvate dehydrogenase complex
    • Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex
    • DLDBP
    • E3 binding protein
    • E3-binding protein
    • E3BP
    • Lipoyl containing pyruvate dehydrogenase complex component X
    • Lipoyl-containing pyruvate dehydrogenase complex component X
    • mitochondrial
    • ODPX_HUMAN
    • OPDX
    • PDHX
    • PDX 1
    • PDX1
    • Pro X
    • proX
    • Pyruvate dehydrogenase complex component X
    • Pyruvate dehydrogenase complex lipoyl containing component X
    • Pyruvate dehydrogenase complex, E3 binding protein subunit
    • Pyruvate dehydrogenase protein X component
    • Pyruvate dehydrogenase protein X component mitochondrial
    see all
  • Function

    Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex.
  • Involvement in disease

    Defects in PDHX are the cause of pyruvate dehydrogenase E3-binding protein deficiency (PDHXD) [MIM:245349].
  • Sequence similarities

    Belongs to the 2-oxoacid dehydrogenase family.
    Contains 1 lipoyl-binding domain.
  • Cellular localization

    Mitochondrion matrix.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of 3 μg ab202213

References

ab202213 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab202213.
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