Description

  • Product name

    Recombinant Human PDLIM5/ENH protein
  • Expression system

    Wheat germ
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVV LSIDGINAQGMTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKGEP KEVVKPVPITSPAVSKVTSTNNMAYNKAPRPFGSVSSPKVTSIPSPSSAF TPAHATTSSHASPSPVAAVTPPLFAASGLHANANLSADQSPSALSAGKTA VNVPRQPTVTSVCSETSQELAEGQRRGSQGDSKQQNGPPRKHIVERYTEF YHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEA DNTKKANNSQEPSPQLASSVASTRSMPESLDSPTSGRPGVTSLTTAAAFK PVGSTGVIKSPSWQRPNQGVPSTGRISNSAAYSGSVAPANSALGQTQPSD QDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCK NTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVINALKQTWHV SCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDM FLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF
    • Amino acids

      1 to 596
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab161071 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.

     This product was previously labelled as PDLIM5

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • ENH
    • ENH1
    • Enigma homolog
    • Enigma like LIM domain protein
    • Enigma like PDZ and LIM domains protein
    • Enigma-like PDZ and LIM domains protein
    • L 9
    • L9
    • LIM
    • PDLI5_HUMAN
    • PDLIM5
    • PDZ and LIM domain 5
    • PDZ and LIM domain protein 5
    see all
  • Function

    May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May restrain postsynaptic growth of excitatory synapses.
  • Tissue specificity

    Heart and skeletal muscle specific. Expression is commonly increased in the brain of patients with bipolar disorder, schizophrenia, and major depression.
  • Sequence similarities

    Contains 3 LIM zinc-binding domains.
    Contains 1 PDZ (DHR) domain.
  • Cellular localization

    Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse > synaptosome. Cytoplasm. Detected both at presynaptic and postsynaptic sites.
  • Information by UniProt

Images

  • ab161071 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab161071 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab161071.
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