Description

  • Product name

    Recombinant human Peroxiredoxin 4 protein
    See all Peroxiredoxin 4 proteins and peptides
  • Biological activity

    Specific activity: approximately 230-310 pmole/min/µg. Enzymatic activity was confirmed by measuring the remaining peroxide after incubation of PRDX 4 and peroxide for 20 min at room temperature. Specific activity is defined as the amount of hydroperoxide that 1 µg of enzyme can reduce at 25°C for 1 minute.
  • Purity

    > 90 % SDS-PAGE.

  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MWETEERPRT REEECHFYAG GQVYPGEASR VSVADHSLHL SKAKISKPAP YWEGTAVIDG EFKELKLTDY RGKYLVFFFY PLDFTFVCPT EIIAFGDRLE EFRSINTEVV ACSVDSQFTH LAWINTPRRQ GGLGPIRIPL LSDLTHQISK DYGVYLEDSG HTLRGLFIID DKGILRQITL NDLPVGRSVD ETLRLVQAFQ YTDKHGEVCP AGWKPGSETI IPDPAGKLKY FDKLN
    • Predicted molecular weight

      29 kDa including tags
    • Amino acids

      29 to 271
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab168036 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 10% Glycerol

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names

    • Antioxidant enzyme 372
    • Antioxidant enzyme AOE372
    • AOE37 2
    • AOE37-2
    • AOE372
    • EC 1.11.1.15
    • Peroxiredoxin IV
    • Peroxiredoxin-4
    • Peroxiredoxin4
    • PRDX 4
    • Prdx4
    • PRDX4_HUMAN
    • PRX 4
    • Prx IV
    • Prx-IV
    • PRX4
    • PrxIV
    • Thioredoxin dependent peroxide reductase A0372
    • Thioredoxin peroxidase
    • Thioredoxin Peroxidase (Antioxidant Enzyme)
    • Thioredoxin peroxidase AO372
    • Thioredoxin-dependent peroxide reductase A0372
    • TRANK
    see all
  • Function

    Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.
  • Sequence similarities

    Belongs to the ahpC/TSA family.
    Contains 1 thioredoxin domain.
  • Cellular localization

    Cytoplasm. Secreted.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab168036 (3µg).

References

ab168036 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab168036.
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