Recombinant Human Pescadillo protein (ab131905)

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Description

  • Product name

    Recombinant Human Pescadillo protein

  • Expression system

    Wheat germ

  • Accession

    O00541

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MGGLEKKKYERGSATNYITRNKARKKLQLSLADFRRLCILKGIYPHEPKH KKKVNKGSTAARTFYLIKDIRFLLHEPIVNKFREYKVFVRKLRKAYGKSE WNTVERLKDNKPNYKLDHIIKERYPTFIDALRDLDDALSMCFLFSTFPRT GKCHVQTIQLCRRLTVEFMHYIIAARALRKVFLSIKGIYYQAEVLGQPIV WITPYAFSHDHPTDVDYRVMATFTEFYTTLLGFVNFRLYQLLNLHYPPKL EGQAQAEAKAGEGTYALDSESCMEKLAALSASLARVVVPATEEEAEVDEF PTDGEMSAQEEDRRKELEAQEKHKKLFEGLKFFLNREVPREALAFIIRSF GGEVSWDKSLCIGATYDVTDSRITHQIVDRPGQQTSVIGRCYVQPQWVFD SVNARLLLPVAEYFSGVQLPPHLSPFVTEKEGDYVPPEKLKLLALQRGED PGNLNESEEEEEEDDNNEGDGDEEGENEEEEEDAEAGSEKEEEARLAALE EQRMEGKKPRVMAGTLKLEDKQRLAQEEESEAKRLAIMMMKKREKYLYQK IMFGKRRKIREANKLAEKRKAHDEAVRSEKKAKKARPE

    • Predicted molecular weight

      94 kDa including tags

    • Amino acids

      1 to 588

Specifications

Our Abpromise guarantee covers the use of ab131905 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

    SDS-PAGE

  • Form

    Liquid

  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • FLJ43790
    • Homo sapiens pescadillo mRNA complete cds
    • PES
    • PES 1
    • pes1
    • PESC_HUMAN
    • Pescadillo (zebrafish) homolog 1 containing BRCT domain
    • Pescadillo homolog
    • Pescadillo homolog 1
    • Pescadillo homolog 1 containing BRCT domain (zebrafish)
    • Pescadillo ribosomal biogenesis factor 1
    see all

  • Function

    Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.

  • Tissue specificity

    Significant levels are detected in a variety of cancer cell lines, including glioblastoma, breast carcinoma, colon carcinoma and cervical carcinoma cells. Levels are abnormally elevated in malignant tumors of astrocytic origin.

  • Sequence similarities

    Belongs to the pescadillo family.
    Contains 1 BRCT domain.

  • Post-translational
    modifications

    Sumoylated.

  • Cellular localization

    Nucleus > nucleolus. Nucleus > nucleoplasm. Chromosome. Appears to localize to the periphery of metaphase chromosomes during mitosis and to the prenucleolar bodies that form in mitotic cells prior to the actual nucleoli.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Pescadillo protein (ab131905)
    SDS-PAGE - Recombinant Human Pescadillo protein (ab131905)
    12.5% SDS-PAGE analysis of ab131905 stained with Coomassie Blue.

References

ab131905 has not yet been referenced specifically in any publications.

Publishing research using ab131905? Please let us know so that we can cite the reference in this datasheet.

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