The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
< 1.000 Eu/µg
% Densitometry. ab175469 was purifed using Ni-NTA chromatography.
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Preparation and Storage
Stability and Storage
Shipped at Room Temperature. Store at +4°C short term (1-2 weeks). Store at -80°C. Avoid freeze / thaw cycle.
Information available upon request.
Add 200 µl of 0.1M Acetate buffer pH=4.0 to prepare a working stock solution of 0.5 mg/mL.
Peptidoglycan recognition protein
Peptidoglycan recognition protein 1
Peptidoglycan recognition protein short
TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein)
Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
Highly expressed in bone marrow. Weak expression found in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils.
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
N-glycosylated. N-glycosylation is required for bactericidal activity.