Recombinant Human PH3 protein (ab164181)

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SDS-PAGE - Recombinant Human PH3 protein (ab164181)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: WB, ELISA

    Description

    • Product name

      Recombinant Human PH3 protein

    • Expression system

      Wheat germ

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MAEAEFKDHSTAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISV YSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHL SSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSVSSLNFFFLDLK F

      • Amino acids

        1 to 151

      • Tags

        GST tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab164181 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Western blot

      ELISA

    • Form

      Liquid

    • Additional notes

       

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • Early development regulator 3
      • Early development regulatory protein 3
      • EDR3
      • Homolog of polyhomeotic 3
      • HPH 3
      • hPH3
      • PH3
      • PHC 3
      • Phc3
      • PHC3_HUMAN
      • Polyhomeotic homolog 3
      • Polyhomeotic homolog 3 (Drosophila)
      • Polyhomeotic-like protein 3
      see all

    • Function

      Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

    • Sequence similarities

      Contains 1 FCS-type zinc finger.
      Contains 1 SAM (sterile alpha motif) domain.

    • Post-translational
      modifications

      Phosphorylated upon DNA damage, probably by ATM or ATR.

    • Cellular localization

      Nucleus.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human PH3 protein (ab164181)
      SDS-PAGE - Recombinant Human PH3 protein (ab164181)
      ab164181 on a 12.5% SDS-PAGE stained with Coomassie Blue.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab164181? Please let us know so that we can cite the reference in this datasheet.

    ab164181 has not yet been referenced specifically in any publications.

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