Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab89857 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    The specific activity of ab89857 was determined to be 70 nmol/min/mg.
  • Applications

    SDS-PAGE

    Functional Studies

  • Form
    Liquid
  • Additional notes

    ab204885 (ZIP Kinase peptide substrate) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • GSD9C
    • PHK gamma LT
    • PHK gamma T
    • Phosphorylase b kinase gamma catalytic chain testis/liver isoform
    • Phosphorylase b kinase gamma catalytic chain, liver/testis isoform
    • Phosphorylase kinase catalytic subunit gamma 2
    • Phosphorylase kinase gamma subunit 2
    • Phosphorylase kinase subunit gamma 2
    • Phosphorylase kinase, gamma 2 (testis)
    • Phosphorylase kinase, gamma 2 (testis/liver)
    • PSK C3
    • Serine/threonine protein kinase PHKG2
    see all
  • Relevance
    Mutations in PHKG2 along with PHKA2 and PHKB, all three different genes of phosphorylase kinase (Phk) subunits, can give rise to glycogen storage disease of the liver. The autosomal-recessive, liver-specific variant of Phk deficiency is caused by mutations in the gene encoding the testis/liver isoform of the catalytic gamma subunit, PHKG2.
  • Cellular localization
    Cytoplasmic

Images

  • Functional Studies - PHKG2 protein (Active) (ab89857)
    Functional Studies - PHKG2 protein (Active) (ab89857)
    Kinase Assay demonstrating specific activity of ab89857
  • SDS-PAGE - PHKG2 protein (Active) (ab89857)
    SDS-PAGE - PHKG2 protein (Active) (ab89857)
    SDS-PAGE showing ab89857 at approximately 70kDa

References

ab89857 has not yet been referenced specifically in any publications.

Publishing research using ab89857? Please let us know so that we can cite the reference in this datasheet.

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