Recombinant Human Phospholipase C beta 1/PLCB1 protein (ab153213)

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Description

  • Product name

    Recombinant Human Phospholipase C beta 1/PLCB1 protein
    See all Phospholipase C beta 1/PLCB1 proteins and peptides

  • Expression system

    Wheat germ

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      VQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQDKFKR LPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGD IPGKEFDTPL

    • Amino acids

      1107 to 1216

    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab153213 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid

  • Additional notes

    This product was previously labelled as Phospholipase C beta 1.

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • 1 phosphatidylinositol 4,5 bisphosphate phosphodiesterase beta 1
    • 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate
    • 1-phosphatidylinositol 4
    • 1-phosphatidylinositol-4
    • 5-bisphosphate phosphodiesterase beta-1
    • EIEE12
    • Inositoltrisphosphohydrolase
    • Monophosphatidylinositol phosphodiesterase
    • Phosphb
    • Phosphoinositidase C
    • Phosphoinositide phospholipase C
    • Phosphoinositide phospholipase C-beta 1
    • Phosphoinositide phospholipase C-beta-1
    • Phospholipase C beta 1 (phosphoinositide-specific)
    • Phospholipase C I
    • Phospholipase C-beta-1
    • Phospholipase C-I
    • PI PLC
    • PLC 1
    • PLC beta 1
    • PLC I
    • PLC-154
    • PLC-beta-1
    • PLC-I
    • PLC154
    • Plcb
    • Plcb1
    • Plcb1 protein
    • PLCB1_HUMAN
    • PLCbeta1
    • Triphosphoinositide phosphodiesterase
    see all

  • Function

    The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

  • Involvement in disease

    Epileptic encephalopathy, early infantile, 12

  • Sequence similarities

    Contains 1 C2 domain.
    Contains 1 PI-PLC X-box domain.
    Contains 1 PI-PLC Y-box domain.

  • Cellular localization

    Nucleus membrane. Cytoplasm. Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Phospholipase C beta 1/PLCB1 protein (ab153213)
    SDS-PAGE - Recombinant Human Phospholipase C beta 1/PLCB1 protein (ab153213)
    ab153213 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab153213 has not yet been referenced specifically in any publications.

Publishing research using ab153213? Please let us know so that we can cite the reference in this datasheet.

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