Recombinant Human PI 3 Kinase p55 gamma protein (ab127108)

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Description

  • Product name

    Recombinant Human PI 3 Kinase p55 gamma protein

  • Purity

    > 80 % SDS-PAGE.
    Purity was determined by densitometry.

  • Expression system

    Baculovirus infected Sf9 cells

  • Accession

    Q8N381

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Predicted molecular weight

      61 kDa including tags

    • Amino acids

      1 to 461

    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127108 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.00
    Preservative: 1.02% Imidazole
    Constituents: 0.002% PMSF, 0.07% Sodium phosphate, 0.004% DTT, 25% Glycerol, 1.76% Sodium chloride

General Info

  • Alternative names

    • DKFZp686P05226
    • FLJ41892
    • OTTHUMP00000009783
    • OTTHUMP00000009786
    • p55
    • p55 gamma
    • P55G_HUMAN
    • p55PIK
    • Phosphatidylinositol 3 kinase regulatory subunit gamma
    • Phosphatidylinositol 3 kinase regulatory subunit polypeptide 3
    • Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55, gamma)
    • Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma
    • Phosphatidylinositol 3-kinase regulatory subunit gamma
    • Phosphoinositide 3 kinase regulatory subunit 3
    • Phosphoinositide 3 kinase regulatory subunit 3 (gamma)
    • Phosphoinositide 3 kinase regulatory subunit polypeptide 3
    • Phosphoinositide 3 kinase, regulatory subunit 3 (p55, gamma)
    • Phosphoinositide 3 kinase, regulatory subunit, polypeptide 3 (p55, gamma)
    • PI3 kinase p85 subunit gamma
    • PI3-kinase regulatory subunit gamma
    • PI3-kinase subunit p55-gamma
    • PI3K regulatory subunit gamma
    • Pik3r3
    • PtdIns 3 kinase p85 gamma
    • PtdIns-3-kinase regulatory subunit gamma
    • PtdIns-3-kinase regulatory subunit p55-gamma
    see all

  • Function

    Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1.

  • Tissue specificity

    Highest levels in brain and testis. Lower levels in adipose tissue, kidney, heart, lung and skeletal muscle.

  • Sequence similarities

    Belongs to the PI3K p85 subunit family.
    Contains 2 SH2 domains.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human PI 3 Kinase p55 gamma protein (ab127108)
    SDS-PAGE - Recombinant Human PI 3 Kinase p55 gamma protein (ab127108)
    SDS-PAGE analysis of ab127108.

References

ab127108 has not yet been referenced specifically in any publications.

Publishing research using ab127108? Please let us know so that we can cite the reference in this datasheet.

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