Product nameRecombinant human PI3 Kinase p110 beta + PI3 Kinase p85 beta protein
Biological activityThe specific activity of ab125571 was determined to be 28 nmol/min/mg.
Purity> 70 % Densitometry.
Purity determined to be >70% by densitometry.
Expression systemBaculovirus infected Sf9 cells
Protein lengthFull length protein
TagsHis tag N-Terminus
Our Abpromise guarantee covers the use of ab125571 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Preservative: 1.02% Imidazole
Constituents: 0.002% PMSF, 0.81% Sodium phosphate, 0.004% DTT, 25% Glycerol, 1.75% Sodium chloride
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- p85 beta
RelevancePI3 Kinase p110 beta: Phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2. PI3 Kinase p85 beta: Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab125571 has been referenced in 1 publication.
- Xiang S et al. Zinc-finger protein 545 is inactivated due to promoter methylation and functions as a tumor suppressor through the Wnt/ß-catenin, PI3K/AKT and MAPK/ERK signaling pathways in colorectal cancer. Int J Oncol 51:801-811 (2017). PubMed: 28677721