Overview

  • Product name

    Recombinant Human Piccolo protein
  • Protein length

    Protein fragment

Description

  • Nature

    Recombinant
  • Source

    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MKKFRVSLVSKVGKQKYVDLNMLSDSENSQHLELHEPPKAVDKAKSPGVD PKQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGS PSVSKKKHGSSKPTDGTKVVSHPITGEIQLQINYDLGNLIIHILQARNLV PRDNNGYSDPFVKVYLLPGRGAEYKRRTKHVQKSLNPEWNQTVIYKSISM EQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTAHLDNTPRWYPLKEQT ESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPDPSKDMQVPTIEKSHSSP GSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAIAAAEAAVQQLRIQ PSKRRK
    • Molecular weight

      65 kDa including tags
    • Amino acids

      85 to 423

Specifications

Our Abpromise guarantee covers the use of ab132154 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml. This protein is best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • ACZ
    • Aczonin
    • Brain-derived HLMN protein
    • DKFZp779G1236
    • KIAA0559
    • Multidomain presynaptic cytomatrix protein
    • PCLO
    • PCLO_HUMAN
    • Piccolo (presynaptic cytomatrix protein)
    • Piccolo, mouse, homolog of
    • Pico
    • Presynaptic cytomatrix protein
    • Protein piccolo
    see all
  • Function

    May act as a scaffolding protein involved in the organization of synaptic active zones and in synaptic vesicle trafficking.
  • Sequence similarities

    Contains 2 C2 domains.
    Contains 1 PDZ (DHR) domain.
  • Domain

    C2 domain 1 is involved in binding calcium and phospholipids. Calcium binds with low affinity but with high specificity and induces a large conformational change.
  • Cellular localization

    Cell junction > synapse. Concentrated at the presynaptic side of synaptic junctions.
  • Information by UniProt

Images

  • SDS-PAGE analysis of ab132154 on a 12.5% gel stained with Coomassie Blue.

References

ab132154 has not yet been referenced specifically in any publications.

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