Name: Recombinant Human PIP5K3 protein
SKU: ab165864

Product name

Recombinant Human PIP5K3 protein
See all PIP5K3 proteins and peptides
Protein length

Full length protein

Nature

Recombinant
Source

Wheat germ
Amino Acid Sequence
- Species
  
  Human
- Sequence
  
  MATDDKTSPTLDSANDLPRSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFV NLFRFNKERAEGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEEL QRRSSALGDLRACTYCRKIALSYAHSTDSNSIGEDLNALSDSACSVSVLD PSEPRTPVGSRKASRNIFLEDDLAWQSLIHPDSSNTPLSTRLVSVQEDAG KSPARNRSASITNLSLDRSGSPMVPSYETSVSPQANRTYVRTETTEDERK ILLDSVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNCIVGKELVNWLIRN GHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRDEYALYRPLQSTEFSET PSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKR TSVSSFQSTVDSDSAASISLNVELDNVNFHIKKPSKYPHVPPHPADQKGR R
- Amino acids
  
  1 to 451
- Tags
  
  proprietary tag N-Terminus

Our Abpromise guarantee covers the use of ab165864 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Applications

ELISA

Western blot
Form

Liquid
Additional notes

Protein concentration is above or equal to 0.05 mg/ml.
Concentration information loading...

Stability and Storage

Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl

Alternative names
- 1 phosphatidylinositol 3 phosphate 5 kinase
- 1 phosphatidylinositol 4 phosphate 5 kinase
- 1-phosphatidylinositol 3-phosphate 5-kinase
- CFD
- epididymis luminal protein 37
- FAB1
- FAB1, S. cerevisiae, homolog of
- FYV1_HUMAN
- FYVE finger containing phosphoinositide kinase
- FYVE finger-containing phosphoinositide kinase
- KIAA0981
- MGC40423
- p235
- Phosphatidylinositol 3 phosphate 5 kinase type III
- Phosphatidylinositol 3 phosphate/phosphatidylinositol 5 kinase type III
- Phosphatidylinositol 3-phosphate 5-kinase
- Phosphatidylinositol 3-phosphate 5-kinase type III
- Phosphatidylinositol 4 phosphate 5 kinase type III
- Phosphoinositide kinase, FYVE finger containing
- PIKfyve
- PIP5K
- PIP5K3
- PIPkin III
- PIPkin-III
- PtdIns(4)P 5 kinase
- Type III PIP kinase
- ZFYVE29
- Zinc finger, FYVE domain containing 29
see all
Function

The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. Plays a role in the biogenesis of endosome carrier vesicles (ECV)/ multivesicular bodies (MVB) transport intermediates from early endosomes.
Involvement in disease

Corneal dystrophy, fleck
Sequence similarities

Contains 1 DEP domain.
Contains 1 FYVE-type zinc finger.
Contains 1 PIPK domain.
Cellular localization

Endosome membrane. Mainly associated with membranes of the late endocytic pathway.
Target information above from: UniProt accession Q9Y2I7 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

SDS-PAGE - Recombinant Human PIP5K3 protein (ab165864)

ab165864 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Datasheet

ab165864 has not yet been referenced specifically in any publications.

Publishing research using ab165864? Please let us know so that we can cite the reference in this datasheet.

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Recombinant Human PIP5K3 protein (ab165864)

Overview

Description

Specifications

Preparation and Storage

General Info

Images

Datasheets and documents

References

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