The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
cAMP dependent protein kinase regulatory subunit alpha 2
cAMP dependent protein kinase regulatory subunit RII alpha
cAMP dependent protein kinase type II alpha regulatory chain
cAMP dependent protein kinase type II alpha regulatory subunit
cAMP-dependent protein kinase type II-alpha regulatory subunit
Protein kinase A RII alpha subunit
Protein kinase cAMP dependent regulatory type II alpha
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
Belongs to the cAMP-dependent kinase regulatory chain family. Contains 2 cyclic nucleotide-binding domains.
Phosphorylated by the activated catalytic chain.
Cytoplasm. Cell membrane. Colocalizes with PJA2 in the cytoplasm and the cell membrane.