Description

  • Product name

    Recombinant human PKC nu/PRKD3 protein
  • Expression system

    Baculovirus infected Sf9 cells
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab60874 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Form

    Liquid
  • Additional notes

    ab204856 (CREB peptide) can be utilized as a substrate for assessing kinase activity

     This product was previously labelled as PKC nu

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.0038% EGTA, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol, 0.87% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names

    • EPK 2
    • EPK2
    • KPCD3_HUMAN
    • nPKC nu
    • nPKC-nu
    • nPKCnu
    • nu
    • PKCnu
    • PKD 3
    • PKD3
    • PRK D3
    • PRKCN
    • PRKD 3
    • Prkd3
    • Protein kinase C
    • Protein kinase C nu
    • Protein kinase C nu type
    • Protein kinase D3
    • Protein kinase EPK 2
    • Protein kinase EPK2
    • Serine threonine protein kinase
    • Serine/threonine protein kinase D3
    • Serine/threonine-protein kinase D3
    see all
  • Function

    Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress.
  • Tissue specificity

    Ubiquitous.
  • Sequence similarities

    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
    Contains 1 PH domain.
    Contains 2 phorbol-ester/DAG-type zinc fingers.
    Contains 1 protein kinase domain.
  • Cellular localization

    Cytoplasm. Membrane. Translocation to the cell membrane is required for kinase activation.
  • Information by UniProt

Images

  • The specific activity of PKC nu/PRKD3 (ab60874) was determined to be 108 nmol/min/mg as per activity assay protocol
  • SDS PAGE analysis of ab60874
  • SDS PAGE analysis of ab60874
  • Sample Kinase Activity Plot.
  • ab60874 on SDS-PAGE, MW ~142 kDa.

References

ab60874 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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