Recombinant Human PLA2G7 protein (ab152087)

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Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level: < 1.000 Eu/µg
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE, HPLC

Description

  • Product name

    Recombinant Human PLA2G7 protein
    See all PLA2G7 proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    Purity is greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.

  • Endotoxin level

    < 1.000 Eu/µg

  • Expression system

    HEK 293 cells

  • Accession

    Q13093

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      FDWQYINPVAHMKSSAWVNKIQVLMAAASFGQTKIPRGNGPYSVGCTDLM FDHTNKGTFLRLYYPSQDNDRLDTLWIPNKEYFWGLSKFLGTHWLMGNIL RLLFGSMTTPANWNSPLRPGEKYPLVVFSHGLGAFRTLYSAIGIDLASHG FIVAAVEHRDRSASATYYFKDQSAAEIGDKSWLYLRTLKQEEETHIRNEQ VRQRAKECSQALSLILDIDHGKPVKNALDLKFDMEQLKDSIDREKIAVIG HSFGGATVIQTLSEDQRFRCGIALDAWMFPLGDEVYSRIPQPLFFINSEY FQYPANIIKMKKCYSPDKERKMITIRGSVHQNFADFTFATGKIIGHMLKL KGDIDSNAAI DLSNKASLAFLQKHLGLHKDFDQWDCLIEGDDENLIPGTNINTTNQHIML QNSSGIEKYN VDHHHHHH

    • Predicted molecular weight

      51 kDa including tags

    • Amino acids

      22 to 441

    • Tags

      His tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab152087 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    HPLC

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 5
    Constituents: Acetic acid buffer, 10% Glycerol (glycerin, glycerine), 0.88% Sodium chloride

General Info

  • Alternative names

    • Platelet-activating factor acetylhydrolase precursor
    • 1 alkyl 2 acetylglycerophosphocholine esterase
    • 1-alkyl-2-acetylglycerophosphocholine esterase
    • 2 acetyl 1 alkylglycerophosphocholine esterase
    • 2-acetyl-1-alkylglycerophosphocholine esterase
    • EC 3.1.1.47 PAF acetylhydrolase PAF 2-acylhydrolase LDL associated phospholipase A2
    • Group VIIA phospholipase A2
    • Group-VIIA phospholipase A2
    • gVIIA PLA2
    • gVIIA-PLA2
    • LDL associated phospholipase A2
    • LDL PLA(2)
    • LDL PLA2
    • LDL-associated phospholipase A2
    • LDL-PLA(2)
    • Lipoprotein associated phospholipase A2
    • LP PLA2
    • PAF 2 acylhydrolase
    • PAF 2 acylhydrolase LDL associated phospholipase A2
    • PAF 2-acylhydrolase
    • PAF acetylhydrolase
    • PAFA_HUMAN
    • PAFAD
    • PAFAH
    • Phospholipase A2, group VII (platelet activating factor acetylhydrolase, plasma)
    • PLA2G7
    • Platelet activating factor acetylhydrolase
    • Platelet activating factor acetylhydrolase 2
    • Platelet-activating factor acetylhydrolase
    see all

  • Function

    Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids.

  • Tissue specificity

    Plasma.

  • Involvement in disease

    Platelet-activating factor acetylhydrolase deficiency
    Asthma
    Atopic hypersensitivity

  • Sequence similarities

    Belongs to the AB hydrolase superfamily. Lipase family.

  • Cellular localization

    Secreted, extracellular space.
  • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab152087? Please let us know so that we can cite the reference in this datasheet.

ab152087 has not yet been referenced specifically in any publications.

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