Recombinant Human POGLUT1 protein (His tag) (ab219279)
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Description
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Product name
Recombinant Human POGLUT1 protein (His tag) -
Purity
> 90 % SDS-PAGE.
ab219279 was purified by using conventional chromatography techniques. -
Endotoxin level
< 1.000 Eu/µg -
Expression system
Baculovirus infected insect cells -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
RQKESGSKWK VFIDQINRSL ENYEPCSSQN CSCYHGVIEE DLTPFRGGIS RKMMAEVVRR KLGTHYQITK NRLYRENDCM FPSRCSGVEH FILEVIGRLP DMEMVINVRD YPQVPKWMEP AIPVFSFSKT SEYHDIMYPA WTFWEGGPAV WPIYPTGLGR WDLFREDLVR SAAQWPWKKK NSTAYFRGSR TSPERDPLIL LSRKNPKLVD AEYTKNQAWK SMKDTLGKPA AKDVHLVDHC KYKYLFNFRG VAASFRFKHL FLCGSLVFHV GDEWLEFFYP QLKPWVHYIP VKTDLSNVQE LLQFVKANDD VAQEIAERGS QFIRNHLQMD DITCYWENLL SEYSKFLSYN VTRRKGYDQI IPKMLKTELL EHHHHHH -
Predicted molecular weight
45 kDa including tags -
Amino acids
24 to 392 -
Tags
His tag C-Terminus -
Additional sequence information
Corresponding to the mature protein without initial signal peptide.
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab219279 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Liquid -
Additional notes
Previously labelled as KTEL1.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.4
Constituents: 90% PBS, 10% Glycerol
General Info
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Alternative names
- C3orf9
- CAP10 like 46 kDa protein
- CAP10 like protein, 46 kDa
see all -
Function
Dual specificity glycosyltransferase. Catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to EGF repeats, such as those found in F7, F9 and NOTCH2, on the consensus sequence C-X-S-X-P-C. Positively regulates Notch signaling without affecting Notch ligand binding. -
Tissue specificity
Expressed in most adult tissues at different intensities. Abundantly expressed in liver. Expressed also in brain, heart, skeletal muscle, spleen, kidney, placenta, lung and peripheral blood leukocyte. Not detectable in colon, thymus and small intestine. Expressed in the epidermis, especially in the upper parts, stratum spinosum and stratum granulosum (at protein level). -
Pathway
Protein modification; protein glycosylation. -
Involvement in disease
Dowling-Degos disease 4 -
Sequence similarities
Belongs to the glycosyltransferase 90 family. -
Cellular localization
Endoplasmic reticulum lumen. - Information by UniProt
Images
Datasheets and documents
References
ab219279 has not yet been referenced specifically in any publications.