Description

  • Product name

    Recombinant Human POLR2L protein
  • Purity

    > 95 % SDS-PAGE.

  • Expression system

    Escherichia coli
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human

Specifications

Our Abpromise guarantee covers the use of ab81843 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.75% Potassium chloride, 0.0154% DTT, 0.316% Tris HCl, 0.00584% EDTA, 20% Glycerol

General Info

  • Alternative names

    • and III subunit ABC5
    • and III subunit RPABC5
    • DNA directed RNA polymerase II polypeptide L
    • DNA-directed RNA polymerase III subunit L
    • DNA-directed RNA polymerases I
    • hRPB7.6
    • hsRPB10b
    • II
    • POLR2L
    • RNA polymerase II 7.6 kDa subunit
    • RNA polymerase II polypeptide L
    • RNA polymerases I
    • RPAB5_HUMAN
    • RPABC5
    • RPB10
    • RPB10 homolog
    • RPB10beta
    • RPB7.6
    see all
  • Function

    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2L/RBP10 is part of the core element with the central large cleft.
  • Sequence similarities

    Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.
  • Cellular localization

    Nucleus.
  • Information by UniProt

References

ab81843 has not yet been referenced specifically in any publications.

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