The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Liprin alpha 4
Protein tyrosine phosphatase receptor type f polypeptide (PTPRF) interacting protein (liprin) alpha 4
Protein tyrosine phosphatase receptor type f polypeptide interacting protein alpha 4
Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4
PTPRF interacting protein alpha 4
PTPRF-interacting protein alpha-4
May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.
Expressed only in the heart, brain, and skeletal muscle.
Belongs to the liprin family. Liprin-alpha subfamily. Contains 3 SAM (sterile alpha motif) domains.
The N-terminal coiled coil regions mediate homodimerization preferentially and heterodimerization type alpha/alpha. The C-terminal, non-coiled coil regions mediate heterodimerization type alpha/beta and interaction with PTPRD, PTPRF and PTPRS.
Cytoplasm. Cell surface. Colocalizes with PTPRF at the cell surface.