Description

  • Product name

    Recombinant Human PPIH protein
    See all PPIH proteins and peptides
  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

    < 1.000 Eu/µg
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MKHHHHHHAS AVANSSPVNP VVFFDVSIGG QEVGRMKIEL FADVVPKTAE NFRQFCTGEF RKDGVPIGYK GSTFHRVIKD FMIQGGDFVN GDGTGVASIY RGPFADENFK LRHSAPGLLS MANSGPSTNG CQFFITCSKC DWLDGKHVVF GKIIDGLLVM RKIENVPTGP NNKPKLPVVI SQCGEM
    • Predicted molecular weight

      20 kDa including tags
    • Amino acids

      2 to 177
    • Tags

      His tag N-Terminus
    • Additional sequence information

      The N terminal His tag is an extra 10 amino acids long.

Specifications

Our Abpromise guarantee covers the use of ab184587 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

    ELISA

    Western blot

  • Mass spectrometry

    LC-MS/MS
  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.4
    Constituent: 100% PBS

    Filtered (0.4 µm)

  • Reconstitution
    Add 200 µl of deionized water to prepare a working stock solution of approximately 0.5 mg/ml.

General Info

  • Alternative names

    • Cyclophilin H
    • CYP-20
    • CypH
    • Peptidyl prolyl cis trans isomerase H
    • Peptidyl-prolyl cis-trans isomerase H
    • Peptidylprolyl isomerase H
    • PPIase H
    • PPIH
    • PPIH_HUMAN
    • RGD1564921
    • Rotamase H
    • Small nuclear ribonucleoprotein particle specific cyclophilin H
    • Small nuclear ribonucleoprotein particle-specific cyclophilin H
    • SnuCyp 20
    • U snRNP associated cyclophilin SnuCyp 20
    • U-snRNP-associated cyclophilin SnuCyp-20
    • USA CYP
    • USA-CYP
    • USACYP
    see all
  • Function

    PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex. May act as a chaperone.
  • Sequence similarities

    Belongs to the cyclophilin-type PPIase family. PPIase H subfamily.
    Contains 1 PPIase cyclophilin-type domain.
  • Cellular localization

    Nucleus speckle. Cytoplasm. Colocalizes with spliceosomal snRNPs. A small proportion may also be cytoplasmic.
  • Information by UniProt

Images

  • 14 % SDS-PAGE separation of Human PPIH

     

    MW: Molecular weight marker

    Lane 1: reduced and boiled sample, 2.5 μg
    Lane 2: non-reduced and non-boiled sample, 2.5 μg

References

ab184587 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab184587.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up