The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
4 1BB mediated signaling molecule
Cyclophilin like 5
Leucine-rich repeat protein 1
LRR repeat protein 1
LRR-repeat protein 1
peptidylprolyl isomerase (cyclophilin) like 5
Peptidylprolyl isomerase like 5
Peptidylprolyl isomerase-like 5
May negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NK-kappaB and JNK1. Probable substrate recognition subunit of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Ubiquitous. Maximal expression was seen in the heart and skeletal muscle and minimal expression seen in the kidney.