The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
p53 induced protein phosphatase 1
p53-induced protein phosphatase 1
Protein phosphatase 1D
protein phosphatase 1D magnesium-dependent delta isoform
Protein phosphatase 2C delta isoform
Protein phosphatase 2C isoform delta
Protein phosphatase magnesium dependent 1 delta
Protein phosphatase magnesium-dependent 1 delta
Protein phosphatase Mg2+/Mn2+ dependent 1D
Protein phosphatase Wip1
Wild type p53 induced phosphatase 1
Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins.
Belongs to the PP2C family. Contains 1 PP2C-like domain.