Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
      O15355
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MGAYLSQPNT VKCSGDGVGA PRLPLPYGFS AMQGWRVSME DAHNCIPELD SETAMFSVYD GHGGEEVALY CAKYLPDIIK DQKAYKEGKL QKALEDAFLA IDAKLTTEEV IKELAQIAGR PTEDEDEKEK VADEDDVDNE EAALLHEEAT MTIEELLTRY GQNCHKGPPH SKSGGGTGEE PGSQGLNGEA GPEDSTRETP SQENGPTAKA YTGFSSNSER GTEAGQVGEP GIPTGEAGPS CSSASDKLPR VAKSKFFEDS EDESDEAEEE EEDSEECSEE EDGYSSEEAE NEEDEDDTEE AEEDDEEEEE EMMVPGMEGK EEPGSDSGTT AVVALIRGKQ LIVANAGDSR CVVSEAGKAL DMSYDHKPED EVELARIKNA GGKVTMDGRV NGGLNLSRAI GDHFYKRNKN LPPEEQMISA LPDIKVLTLT DDHEFMVIAC DGIWNVMSSQ EVVDFIQSKI SQRDENGELR LLSSIVEELL DQCLAPDTSG DGTGCDNMTC IIICFKPRNT AELQPESGKR KLEEVLSTEG AEENGNSDKK KKAKRD
    • Molecular weight
      61 kDa including tags
    • Amino acids
      1 to 546
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab168041 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Specific activity: >5,000 units/mg. One unit will hydrolyze 1 nmole of pnitrophenylphosphatate (pNPP) per minute at 37°C, pH 7.5 using 10 mM of substrate.
  • Applications

    SDS-PAGE

    Functional Studies

  • Purity
    >= 85 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.002% PMSF, 0.02% DTT, 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • MGC1675
    • MGC2870
    • OTTHUMP00000123426
    • PP2C
    • PP2C gamma
    • PP2C-gamma
    • PP2CG
    • PP2Cgamma
    • PPM1G
    • PPM1G_HUMAN
    • PPP2CG
    • Protein phosphatase 1C
    • Protein phosphatase 1G
    • Protein phosphatase 2 catalytic subunit gamma isoform
    • Protein phosphatase 2C gamma isoform
    • Protein phosphatase 2C isoform gamma
    • Protein phosphatase magnesium dependent 1 gamma
    • Protein phosphatase magnesium-dependent 1 gamma
    • Protein phosphatase Mg2+/Mn2+ dependent 1G
    see all
  • Tissue specificity
    Widely expressed. Most abundant in testis, skeletal muscle, and heart.
  • Sequence similarities
    Belongs to the PP2C family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

Images

  • SDS-PAGE - PPM1G protein (Active) (ab168041)
    SDS-PAGE - PPM1G protein (Active) (ab168041)
    15% SDS-PAGE analysis of ab168041 (3µg).

References

ab168041 has not yet been referenced specifically in any publications.

Publishing research using ab168041? Please let us know so that we can cite the reference in this datasheet.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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