Overview

  • Product name
    Recombinant Human PPM1L protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MIEDTMTLLSLLGRIMRYFLLRPETLFLLCISLALWSYFFHTDEVKTIVK SSRDAVKMVKGKVAEIMQNDRLGGLDVLEAEFSKTWEFKNHNVAVYSIQG RRDHMEDRFEVLTDLANKTHPSIFGIFDGHGGETAAEYVKSRLPEALKQH LQDYEKDKENSVLSYQTILEQQILSIDREMLEKLTVSYDEAGTTCLIALL SDKDLTVANVGDSRGVLCDKDGNAIPLSHDHKPYQLKERKRIKRAGGFIS FNGSWRVQGILAMSRSLGDYPLKNLNVVIPDPDILTFDLDKLQPEFMILA SDGLWDAFSNEEAVRFIKERLDEPHFGAKSIVLQSFYRGCPDNITVMVVK FRNSSKTEEQ
    • Amino acids
      1 to 360
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab165634 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • EC 3.1.3.16
    • in phosphatase 1 (formerly 2C) like
    • MGC132545
    • MGC132547
    • OTTHUMP00000213920
    • OTTHUMP00000213921
    • PP2C epsilon
    • PP2C-epsilon
    • PP2CE
    • PPM1 like
    • PPM1-LIKE
    • PPM1L
    • PPM1L_HUMAN
    • Protein phosphatase 1 (formerly 2C)-like
    • Protein phosphatase 1 like
    • Protein phosphatase 1-like
    • Protein phosphatase 1L
    • Protein phosphatase 2C epsilon isoform
    • Protein phosphatase 2C isoform epsilon
    • Protein phosphatase, Mg2+/Mn2+ dependent, 1L
    see all
  • Function
    Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6.
  • Tissue specificity
    Ubiquitous. Highly expressed in heart, placenta, lung, liver, kidney and pancreas.
  • Sequence similarities
    Belongs to the PP2C family.
    Contains 1 PP2C-like domain.
  • Cellular localization
    Membrane.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human PPM1L protein (ab165634)
    SDS-PAGE - Recombinant Human PPM1L protein (ab165634)
    ab165634 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab165634 has not yet been referenced specifically in any publications.

Publishing research using ab165634? Please let us know so that we can cite the reference in this datasheet.

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