Recombinant Human PPP2R2A protein (ab159172)

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Description

  • Product name

    Recombinant Human PPP2R2A protein

  • Expression system

    Wheat germ

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MAGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGG RVVIFQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIR WLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVT TLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRI NLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGT IRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYM MTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCW NGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCAS GKRKKDEISVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKVN

    • Amino acids

      1 to 447

    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab159172 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid

  • Additional notes

     

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • 2ABA_HUMAN
    • Alpha isoform of regulatory subunit B55 protein phosphatase 2
    • B55A
    • B55ALPHA
    • calcineurin
    • PP2A subunit B B alpha isoform
    • PP2A subunit B B55 alpha isoform
    • PP2A subunit B isoform alpha
    • PP2A subunit B isoform B55-alpha
    • PP2A subunit B isoform PR55-alpha
    • PP2A subunit B isoform R2-alpha
    • PP2A subunit B PR55 alpha isoform
    • PP2A subunit B R2 alpha isoform
    • PPP2R2A
    • PR52A
    • PR55A
    • Protein phosphatase 2 (formerly 2A) regulatory subunit B (PR 52) alpha isoform
    • Protein phosphatase 2 (formerly 2A), regulatory subunit B (PR52), alpha isoform
    • Protein phosphatase 2 regulatory subunit B alpha
    • Protein phosphatase 2 regulatory subunit B alpha isoform
    • Protein phosphatase 2 regulatory subunit Balpha
    • Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
    • Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
    • Testicular tissue protein Li 156
    see all

  • Function

    The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

  • Tissue specificity

    Expressed in all tissues examined.

  • Sequence similarities

    Belongs to the phosphatase 2A regulatory subunit B family.
    Contains 7 WD repeats.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human PPP2R2A protein (ab159172)
    SDS-PAGE - Recombinant Human PPP2R2A protein (ab159172)
    ab159172 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

This product has been referenced in:

  • Játiva S  et al. Cdc14 activation requires coordinated Cdk1-dependent phosphorylation of Net1 and PP2A-Cdc55 at anaphase onset. Cell Mol Life Sci N/A:N/A (2019). Read more (PubMed: 30927017) »
See 1 Publication for this product

Publishing research using ab159172? Please let us know so that we can cite the reference in this datasheet.

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