Overview

  • Product name

    Recombinant Human PRA1 protein
  • Protein length

    Full length protein

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Molecular weight

      21 kDa
    • Amino acids

      1 to 185
    • Tags

      His-DHFR tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127119 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration.

General Info

  • Alternative names

    • PRA1 domain family 1
    • PRA1 family protein 1
    • PRAF1
    • PRAF1_HUMAN
    • prenylated Rab acceptor 1
    • Prenylated Rab acceptor protein 1
    • Rab acceptor 1 (prenylated)
    • RABAC1
    • YIP3
    see all
  • Function

    General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI.
  • Tissue specificity

    Ubiquitous. Strongest expression found in placenta, pituitary gland, kidney, lung and stomach.
  • Sequence similarities

    Belongs to the PRA1 family.
  • Developmental stage

    In fetal tissues, it is more abundant in kidney and lung.
  • Cellular localization

    Cell membrane. Cytoplasm. Golgi apparatus. Cytoplasmic vesicle > secretory vesicle > synaptic vesicle. According to some authors, it is an integral membrane protein, while others showed that it is cytoplasmic and membrane-associated to Golgi and synaptic vesicles.
  • Information by UniProt

References

ab127119 has not yet been referenced specifically in any publications.

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