Recombinant Human PRCP protein (ab159182)

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Description

  • Product name

    Recombinant Human PRCP protein
    See all PRCP proteins and peptides

  • Expression system

    Wheat germ

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSV LYFQQKVDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFC NNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQA LADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGAL AASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRSWDAINRLSNT GSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQP LPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETA TSSPGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGV RPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTI SEGAHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQH

    • Amino acids

      1 to 496

    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab159182 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form

    Liquid

  • Additional notes

     

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • Angiotensinase C
    • HUMPCP
    • Lysosomal carboxypeptidase C
    • Lysosomal Pro X carboxypeptidase
    • Lysosomal Pro-X carboxypeptidase
    • MGC2202
    • PCP
    • PCP_HUMAN
    • PRCP
    • Proline carboxypeptidase
    • Prolylcarboxypeptidase
    • Prolylcarboxypeptidase (angiotensinase C)
    • prolylcarboxypeptidase isoform 1 preproprotein
    see all

  • Function

    Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.

  • Tissue specificity

    Highest levels in placenta, lung and liver. Also present in heart, brain, pancreas and kidney.

  • Sequence similarities

    Belongs to the peptidase S28 family.

  • Cellular localization

    Lysosome.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human PRCP protein (ab159182)
    SDS-PAGE - Recombinant Human PRCP protein (ab159182)
    ab159182 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab159182 has not yet been referenced specifically in any publications.

Publishing research using ab159182? Please let us know so that we can cite the reference in this datasheet.

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