Key features and details
- Expression system: Wheat germ
- Suitable for: SDS-PAGE, WB, ELISA
Product nameRecombinant Human PRDM1/Blimp1 protein
Expression systemWheat germ
Protein lengthProtein fragment
SequenceMKMDMEDADMTLWTEAEFEEKCTYIVNDHPWDSGADGGTSVQAEASLPRN LLFKYATNSEEVIGVMSKEYIPKGTRFGPLIGEIYTNDTVPKNANRKYFW RIYSRGELH
Predicted molecular weight38 kDa including tags
Amino acids1 to 109
Our Abpromise guarantee covers the use of ab152234 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.31% Glutathione, 0.79% Tris HCl
- B Lymphocyte Induced Maturation Protein 1
- Beta interferon gene positive regulatory domain I binding factor
- Beta-interferon gene positive regulatory domain I-binding factor
FunctionTranscriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene (PubMed:1851123). Drives the maturation of B-lymphocytes into Ig secreting cells (PubMed:12626569).
Sequence similaritiesBelongs to the class V-like SAM-binding methyltransferase superfamily.
Contains 4 C2H2-type zinc fingers.
Contains 1 SET domain.
modificationsSumoylation at Lys-816 by PIAS1 augments transcriptional repressor activity, and is critical for plasma cell differentiation.
Ubiquitinated by the SCF(FBXO11) complex, leading to its degradation by the proteasome.
Cellular localizationNucleus. Cytoplasm.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab152234 has not yet been referenced specifically in any publications.