Recombinant Human Prohibitin protein (ab140551)

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Description

  • Product name

    Recombinant Human Prohibitin protein
    See all Prohibitin proteins and peptides

  • Purity

    > 85 % SDS-PAGE.
    ab140551 is purified using conventional chromatography techniques.

  • Expression system

    Escherichia coli

  • Accession

    P35232

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MGSSHHHHHH SSGLVPRGSH MAAKVFESIG KFGLALAVAG GVVNSALYNV DAGHRAVIFD RFRGVQDIVV GEGTHFLIPW VQKPIIFDCR SRPRNVPVIT GSKDLQNVNI TLRILFRPVA SQLPRIFTSI GEDYDERVLP SITTEILKSV VARFDAGELI TQRELVSRQV SDDLTERAAT FGLILDDVSL THLTFGKEFT EAVEAKQVAQ QEAERARFVV EKAEQQKKAA IISAEGDSKA AELIANSLAT AGDGLIELRK LEAAEDIAYQ LSRSRNITYL PAGQSVLLQL PQ

    • Predicted molecular weight

      32 kDa including tags

    • Amino acids

      1 to 272

    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab140551 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride

General Info

  • Alternative names

    • Epididymis luminal protein 215
    • Epididymis secretory sperm binding protein Li 54e
    • HEL 215
    • HEL S 54e
    • PHB
    • PHB_HUMAN
    • PHB1
    • Prohibitin
    see all

  • Function

    Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.

  • Tissue specificity

    Widely expressed in different tissues.

  • Sequence similarities

    Belongs to the prohibitin family.

  • Developmental stage

    Levels of expression in fibroblasts decrease heterogeneously during cellular aging.

  • Cellular localization

    Mitochondrion inner membrane.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Prohibitin protein (ab140551)
    SDS-PAGE - Recombinant Human Prohibitin protein (ab140551)

    15% SDS-PAGE analysis of ab140551 (3µg).

References

ab140551 has not yet been referenced specifically in any publications.

Publishing research using ab140551? Please let us know so that we can cite the reference in this datasheet.

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