Overview

Description

  • Nature

    Recombinant
  • Source

    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFA VLVTGLAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMT FFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLF CALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIF LCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAV CSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVF QRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLS AWGEGQVEPLPPTQQSSGSAVGTSSKAEASVACSLC
    • Molecular weight

      67 kDa including tags
    • Amino acids

      1 to 386

Specifications

Our Abpromise guarantee covers the use of ab132114 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 ug/ul
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • IP
    • PGI receptor
    • PGI2 receptor
    • PI2R_HUMAN
    • PRIPR
    • Prostacyclin receptor
    • Prostaglandin I2 (prostacyclin) receptor (IP)
    • Prostaglandin I2 receptor
    • Prostanoid IP receptor
    • Ptgir
    see all
  • Function

    Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications

    Palmitoylation of either Cys-308 or Cys-311 is sufficient to maintain functional coupling to G(s) and signaling.
    Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C.
  • Cellular localization

    Cell membrane.
  • Information by UniProt

Images

  • 12.5% SDS-PAGE analysis of ab132114, stained with Coomassie Blue.

References

ab132114 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab132114.
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