Description

  • Product name

    Recombinant Human Prostate Secretory Protein/PSP
  • Expression system

    Wheat germ
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MNVLLGSVVIFATFVTLCNASCYFIPNEGVPGDSTRKCMDLKGNKHPINS EWQTDNCETCTCYETEISCCTLVSTPVGYDKDNCQRIFKKEDCKYIVVEK KDPKKTCSVSEWII
    • Predicted molecular weight

      39 kDa including tags
    • Amino acids

      1 to 114

Specifications

Our Abpromise guarantee covers the use of ab114477 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • Beta microseminoprotein [Precursor]
    • Beta-microseminoprotein
    • HPC 13
    • HPC13
    • IGBF
    • Immunoglobulin binding factor
    • Immunoglobulin-binding factor
    • microseminoprotein beta
    • Msmb
    • MSMB_HUMAN
    • MSP
    • MSPB
    • PN 44
    • PN44
    • Prostate secreted seminal plasma protein
    • Prostate secretory protein of 94 amino acids
    • Prostate secretory protein PSP94
    • PRPS
    • PRSP
    • PSP
    • PSP 57
    • PSP-94
    • PSP57
    • PSP94
    • Seminal plasma beta inhibin
    • Seminal plasma beta-inhibin
    see all
  • Tissue specificity

    Strongly expressed in prostate, liver, kidney, breast and penis. Also expressed in pancreas, esophagus, stomach, deodenum, colon, trachea, lung, salivary glands and fallopian tube. PSP94 is expressed in lung and breast, whereas PSP57 is found in kidney and bladder.
  • Involvement in disease

    Defects in MSMB are the cause of susceptibility to prostate cancer hereditary type 13 (HPC13) [MIM:611928]. It is a condition associated with familial predisposition to cancer of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma.
  • Sequence similarities

    Belongs to the beta-microseminoprotein family.
  • Cellular localization

    Secreted. Sperm surface.
  • Information by UniProt

Images

  • 12.5% SDS-PAGE showing ab114477 at approximately 38.65kDa stained with Coomassie Blue.

References

ab114477 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab114477.
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