Recombinant Human Proteasome 20S beta 7/PSMB7 protein (ab123208)

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Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
      Q99436
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MTTIAGVVYK DGIVLGADTR ATEGMVVADK NCSKIHFISP NIYCCGAGTA ADTDMTTQLI SSNLELHSLS TGRLPRVVTA NRMLKQMLFR YQGYIGAALV LGGVDVTGPH LYSIYPHGST DKLPYVTMGS GSLAAMAVFE DKFRPDMEEE EAKNLVSEAI AAGIFNDLGS GSNIDLCVIS KNKLDFLRPY TVPNKKGTRL GRYRCEKGTT AVLTEKITPL EIEVLEETVQ TMDTS
    • Molecular weight
      28 kDa including tags
    • Amino acids
      44 to 277
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab123208 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Mass Spectrometry

    SDS-PAGE

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 80 % SDS-PAGE.
    ab123208 is purified by using conventional chromatography. Purity is > 80% by SDS-PAGE.
  • Form
    Liquid
  • Additional notes

     This product was previously labelled as Proteasome 20S beta 7

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol

General Info

  • Alternative names
    • Macropain chain Z
    • Multicatalytic endopeptidase complex chain Z
    • Proteasome (prosome macropain) subunit beta type 7
    • Proteasome beta 7 subunit
    • Proteasome catalytic subunit 2
    • Proteasome subunit alpha
    • Proteasome subunit beta 7
    • Proteasome subunit beta type-7
    • Proteasome subunit Z
    • PSB7_HUMAN
    • PSMB7
    • PUP1
    • Z
    see all
  • Function
    The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the trypsin-like activity.
  • Tissue specificity
    Expressed at a low level in colonic mucosa. Up-regulated in colorectal cancer tissues.
  • Sequence similarities
    Belongs to the peptidase T1B family.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Proteasome 20S beta 7/PSMB7 protein (ab123208)
    SDS-PAGE - Recombinant Human Proteasome 20S beta 7/PSMB7 protein (ab123208)
    15% SDS-PAGE analysis of ab123208 (3µg).

References

ab123208 has not yet been referenced specifically in any publications.

Publishing research using ab123208? Please let us know so that we can cite the reference in this datasheet.

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