The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
26S protease subunit S5 basic
26S proteasome non-ATPase regulatory subunit 5
26S proteasome subunit S5B
Protease 26S, subunit 5B
Proteasome (prosome, macropain) 26S subunit, non ATPase, 5
Proteasome 19S S5B
Proteasome 26S subunit, non ATPase, 5
Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5.
Belongs to the proteasome subunit S5B/HSM3 family.
Rich in dileucine repeats, which have been implicated in trafficking of a variety of transmembrane proteins.